Hemostasis in Liver Injuries: An Experimental Study

نویسندگان

چکیده

Introduction. Bleeding in liver injuries is observed during natural disasters, massive injuries, military field conditions and under other circumstances. The vital need for surgical treatment these cases obvious. As a rule, time assistance limited, operations are performed by surgeons who do not have sufficient experience. Intraoperative hemostasis methods always effective. search intraoperative has stopped many decades. Experimental study of the effect new agents that allow reliable damage relevant medical science practice.Materials methods. experimental included 116 white Wistar rats both sexes weighed 230 25 g 30 Chinchilla rabbits 2.5-3.5 kg. following parameters were identified experiments vivo: duration bleeding simulated injury without use hemostatics with alufer viscostat preparations. A morphological regenerative process was carried out on 1st - 14th day after injury. biopsy material fixed 10% formalin solution. Staining histological sections hematoxylin eosin, as well Prussian blue (according to Max Perls) detect iron compounds tissues.Results. It revealed implementation preparation accompanied decrease circulatory disorders (edema, hemorrhages); characterized more pronounced formation connective tissue area drug ​​application, which partially retained (taking into account interval study) at site application.

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ژورنال

عنوان ژورنال: Vestnik of Experimental and Clinical Surgery

سال: 2021

ISSN: ['2070-478X', '2409-143X']

DOI: https://doi.org/10.18499/2070-478x-2021-14-1-47-52